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About Us  | Clinical Advisory Board
 
Francis Berenbaum, M.D., Ph.D
  Dr. Berenbaum is the leader of "Ageing, Inflammation and Osteoarthritis" group at Pierre & Marie Curie University and is the Director of the Department of Rheumatology at AP-HP Saint-Antoine Hospital in Paris, France. He is a member of several national and international medical societies, including the American College of Rheumatology, and is former-President (2011-2012) of OARSI (Osteoarthritis Research Society International). He is Associate Editor of the Annals of the Rheumatic Diseases and on the editorial boards of Nature Reviews in Rheumatology, Arthritis Research and Therapy and Joint Bone Spine. Dr Berenbaum's basic research interests include the role of inflammation in osteoarthritis and the understanding of relationships between metabolic diseases and osteoarthritis. His clinical research focuses on hand osteoarthritis and on new targeted therapies for treating symptoms and structural changes in osteoarthritis. Francis Berenbaum received his MD in Rheumatology in 1993, followed by a PhD in 1995.

Virginia Byers Kraus, M.D., Ph.D.
 

 

 

Dr. Kraus is Professor of Medicine at Duke University and a practicing Rheumatologist with 20 years experience in Osteoarthritis research. She headed the NIHAMS/NIA OA Biomarker Network from 2003 to 2006 and is now the co-PI with Dr. Linda Sandell, on the U13 conference grant series of three Osteoarthritis Biomarker Global Initiative Workshops. She also served as the Chair of the OARSI-FDA Biomarkers Working Group. She directs the Biological Studies Core Laboratory for the Duke Aging Center and the Biomarkers Core Laboratory for the Duke Program Project Grant in Osteoarthritis. Dr. Kraus supervises a laboratory devoted to translational research to advance the understanding of the pathogenesis of osteoarthritis and to contribute to definitive remittive therapies for the disease. She has a special interest in strategies to reduce the incidence of post-traumatic osteoarthritis. The work in the laboratory focuses on the discovery and validation of novel in vitro and in vivo biochemical and genetic biomarkers for early osteoarthritis detection, prediction of progression, and monitoring of disease status and severity. In addition she is President Elect and Executive Committee member of OARSI to promote global research toward the prevention and treatment of osteoarthritis.
 
David Hunter, M.D., Ph.D
  .Dr. David Hunter is Professor of Medicine at University of Sydney and Consultant Rheumatologist at Royal North Shore Hospital and North Sydney Orthopedic and Sports Medicine Centre. Since receiving his Ph.D. in 2001 from the University of Sydney Dr. Hunter has gained world wide recognition as one of the leading researchers in osteoarthritis. This reputation arises from his significant contributions in the area of clinical research in osteoarthritis. In his current work Dr. Hunter is investigating a number of key elements in osteoarthritis including the epidemiology of osteoarthritis, genetic epidemiology of osteoarthritis, the role of biomarkers in understanding osteoarthritis aetiopathogenesis, the application of imaging to better understand structure and function with application to both epidemiologic research and clinical trials, the application of novel therapies in disease management and heath service system delivery of chronic disease management. He is a board member of the International Osteoarthritis Research Society and founded the Osteoarthritis Imaging Group. He is an advisory editor for the premier rheumatology journal Arthritis and Rheumatism, and an associate editor for Osteoarthritis and Cartilage, Arthritis Care and Research, and BMC Musculoskeletal Disorders. He is a member of the Australian College of Physicians, Australian Rheumatology Association, American College of Rheumatology, Orthopaedic Research Society and International Osteoarthritis Research Society.
Lee S. Simon, M.D., F.A.C.P., F.A.C.R.
 

Dr. Simon has been a clinical Rheumatologist for 25 years and is a Principal in SDG LLC, a consulting firm helping companies to create successful drug development programs, and also serves as Head regulatory consultant to Leerink Swann/Medacorp. Dr. Simaon has been the Division Director of Analgesic, Anti-inflammatory and Ophthalmologic Drug Products (DAAODP), within the Center for Drug Evaluation and Research (CDER), FDA. He has served on and has been the Acting Chair of the Arthritis Advisory Committee of the DAAODP. He has also served on the advisory committees for the Division of Over the Counter Drugs, Center for Devices, and for the Division of Hematologic and Gastroenterologic Drug Products. He is a fellow of the American College of Physicians and the American College of Rheumatology.  Dr. Simon has had extensive experience in drug development, including drugs and other therapeutics used for pain, anti-inflammatory effects, alteration of bone turnover, as well as modifying inflammatory disease states. He has served on the Board of Directors of the American College of Rheumatology (ACR), served as the Chair of Education for both the ACR and the National Arthritis Foundation. He was an Associate Professor of Medicine at Harvard Medical School, an Associate Chief of Medicine, Beth Israel Deaconess Medical Center (BIDMC), and Chair of Rehabilitation Services at the Deaconess Hospital, Harvard Medical School before joining the FDA. 


 

 
 
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