TransPharma Medical's formulation team has gained a vast amount of experience and expertise to efficiently formulate compounds to be delivered using the ViaDerm system. Depending on the compound’s characteristics, the drug patch used could be one of the following:

• A patch carrying a hydrophilic formulation
• A unique patch for proteins
• A non-altered standard existing patch

Breakthroughs in Drug Patch Technology
TransPharma Medical is pioneering a unique printed patch for transdermal delivery of proteins, which will complement its ViaDerm delivery technology.

The printed patch involves spreading a drug molecule in a dry form on a backing liner. The powder patch stays in its dry form, which improves stability and prolongs shelf life, right up until the time it is administered. As soon as the RF MicroChannels have been created, and the printed patch is applied, extra-cellular fluid, released by the body through the microchannels, comes in contact with the powder and dissolves it to form a saturated solution or suspension with an extremely sharp concentration gradient, resulting in efficient delivery.

The Printed Patch Technology, a proprietary TransPharma Medical technology, brings together the advantages of a dry dosage form and the special features of the hydrophilic channels. It is being specifically developed to provide a solution to the challenge of transdermal delivery of proteins and other macromolecules.